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MHRA Drug Safety Updates

MHRA Drug Safety Updates

MHRA Yellow Card Scheme: please help to reverse the decline in reporting of suspected adverse drug reactions 

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application/pdfDrug Safety Update January 2018.pdf (301KB)09/01/2018Download
 Daclizumab (Zinbryta▼) and risk of severe liver injury. Recombinant human erythropoietins: very rare risk of severe cutaneous adverse reactions. Drug-name confusion: reminder to be vigilant for... 
application/pdfDrug Safety Update MHRA December 2017 (421KB)15/12/2017Download
 Cladribine (Litak, Leustat) for leukaemia, Gadolinium-containing contrast agents, Radium-223 dichloride (Xofigo▼), Eluxadoline (Truberzi ▼): 
application/pdfDrug Safety Update MHRA November 2017 pdf. (357KB)27/11/2017Download
 Gentamicin: potential for histamine-related adverse drug reactions with some batches, Quinine: reminder of dose-dependent QT-prolonging effects; updated interactions, Oral tacrolimus products:... 
application/pdfDrug Safety Update MHRA October pdf.pdf (246KB)27/10/2017Download
 Methylprednisolone inj medicines containing lactose Gabapentin: risk of severe respiratory depression Clozapine: reminder of potentially fatal risk of intestinal obstruction, 
application/pdfDrug safety Update MHRA Sept-pdf.pdf (230KB)27/10/2017Download
 Miconazole (Daktarin) OTC oral gel contra-indications in patients taking warfarin. Loperamide: reports of serious cardiac adverse reactions with high doses of loperamide associated with abuse or... 
application/pdfDrug Safety Update MHRA August PDF.pdf (260KB)27/10/2017Download
 Ibrutinib (Imbruvica▼): reports of ventricular tachyarrhythmia; risk of hepatitis B reactivation and of opportunistic infections Corticosteroids: risk of central serous chorioretinopathy with... 
application/pdfDrug Safety Update MHRA July 2017 PDF.pdf (229KB)26/07/2017Download
 Daclizumab (Zinbryta▼) and risk of severe liver injury, Bendamustine (Levact, Nivolumab (Opdivo▼), pembrolizumab (Keytruda▼): reports of organ transplant rejection 
application/pdfDrug safety Update June 2017 PDF.pdf (147KB)22/06/2017Download
 Denosumab reports of osteonecrosis of the external auditory canal, brimoniudine gel: risk of cardiovascular effects: not to be applied to damaged skin 
application/pdfDrug Safety Update May 2017 .pdf (200KB)26/05/2017Download
 Finasteride: rare reports of depression and suicidal thoughts 
application/pdfDrug Safety Update April 2017.pdf (132KB)28/04/2017Download
 Valproate and developmental disorders: new alert asking for patient review and further consideration of risk minimisation measures 
application/pdfDrug Safety Update March 2017.pdf (104KB)31/03/2017Download
application/pdfDrug Safety Update February 2017 (86KB)21/02/2017Download
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